Human genome contains about 23,000 genes that encode for proteins.
3,000 of them are estimated to be druggable targets for therapeutic interventions.
Only about 3oo of them, or 10%, are currently targets of approved drugs.
There’s no lack of targets,
the question is target for what.
The matching of a target to a condition determines the fate of that drug development effort. A same target could be worth billions in one condition but worthless in another. While most of drug targets have monogamous effect, especially in the monogenic conditions such as sickle cell anemia, cystic fibrosis, most drug targets are promiscuous, hitting one target generates myriad of effects, which generates side effect when applied to a condition, thus limiting its pharmacological doses and capping potential efficacy in treating the intended condition.
Geneware helps to identify target to condition matching so interventions generate precise therapeutic effects that are intended.